Perfumes may harm body’s natural protective cloud: Study
Earlier studies have linked perfume use to headaches, asthma, allergic reactions, eczema, and sinus issues

For the first time, a groundbreaking scientific study has revealed that perfume components can interfere with an invisible protective “cloud” surrounding human skin — one that plays a vital role in purifying the air we breathe and maintaining our overall health.
The study, conducted by researchers from the University of California and the Max Planck Institute for Physics in Germany, refers to this atmospheric layer as an “oxidation field.” It forms when natural oils on our skin, such as squalene — a substance that helps maintain skin elasticity — react with ozone in the air through a process known as ozonolysis. This reaction produces highly reactive molecules called hydroxyl radicals, which help form a dynamic, protective “bubble” around the human body.
Described as nature’s “air cleaners,” hydroxyl radicals are crucial because they neutralize harmful airborne toxins and pollutants before they enter the respiratory system. The presence of these radicals is linked to better lung function, reduced inflammation, decreased biological stress, improved cardiovascular health, and lower risk of hypertension.
However, the study found that this beneficial shield can be significantly disrupted by the use of perfumes and scented body lotions. Tests conducted on four volunteers showed that applying perfume reduced the presence of this protective cloud by 86%, while scented moisturizers caused a 34% reduction.
The researchers caution that although perfumes may not be directly toxic, their impact on this natural chemical barrier compromises the skin’s ability to protect the body from harmful environmental elements. This discovery challenges previous assumptions that perfumes are harmless when used on skin.
In support of these findings, the researchers also cited earlier studies linking perfume use to headaches, asthma, allergic reactions, eczema, and sinus issues. Additionally, a British study warned against applying perfume directly to the skin, as it can cause persistent dark spots that may require laser treatment for removal.
In light of these findings, scientists encourage further exploration into how personal care products affect the skin’s chemical interactions with the environment — and urge consumers to reconsider their use of fragranced products in daily routines.