Malarial fever infected nearly 200 million people worldwide in 2013 and caused the death of over 500,000 people, most of them children in Africa.
The malaria parasite, Plasmodium, grows in mosquitoes and is transmitted to people when the female insect bites a person. Symptoms include fever, headache and vomiting. They usually appear 10-15 days after the mosquito bite. In the human body, it multiplies in the liver and infects red blood cells. If not treated, malaria can quickly disrupt the blood supply to vital organs and become life-threatening.
Now, for the first-time, scientists have uncovered the role played by cyclin, a protein that plays a significant role in growth of the malaria parasite in mosquitoes. Researchers believe the discovery will increase understanding of how the malaria parasite thrives inside its insect and
Cyclin plays a key role in the timing and control of cell division in the parasite leading to its multiplication. Scientists observed that deleting this protein in the parasite led to several abnormalities that impaired cell division in Plasmodium. Researchers believe that their study will definitely further the understanding of parasite cell.